Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ SR 10067
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Selective Rev-Erbα/β agonist; anxiolytic
| CAS | 1380548-02-6 |
|---|---|
| Chemical Name or Material | [3-[[4-(1,1-Dimethylethoxy)phenoxy]methyl]-3,4-dihydro-2(1H)-isoquinolinyl]-1-naphthalenylmethanone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C31H31NO3 |
| Formula Weight | Observed MW: 465.58 |
| Assay Percent Range | >98% |
Tocris Bioscience™ SR 27897
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Potent and selective CCK1 antagonist
| Inhibitors | SR 27897 |
|---|---|
| Product Type | SR 27897 |
| Molecular Weight (g/mol) | 411.86 |
| Purity | >99% |
Tocris Bioscience™ WM 8014
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Potent and selective KAT6A and KAT6B inhibitor
Tocris Bioscience™ B02
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RAD51 recombinase inhibitor
| CAS | 1290541-46-6 |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at 4°C |
| Synonym | 3-(Phenylmethyl)-2-[(1E)-2-(3-pyridinyl)ethenyl]-4(3H)-quinazolinone |
| Molecular Formula | C22H17N3O |
| Formula Weight | 339.4 |
Tocris Bioscience™ SW 033291
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation
| Target | Dehydrogenase Inhibitors |
|---|---|
| CAS | 459147-39-8 |
| Purity | >98% |
| Chemical Name or Material | 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H20N2OS3 |
| Formula Weight | 412.59 |
Tocris Bioscience™ CU CPT 22
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CAS: 1416324-85-0 Molecular Formula: C19H22O7
| CAS | 1416324-85-0 |
|---|---|
| Molecular Formula | C19H22O7 |
Tocris Bioscience™ TAK 375
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Greener Choice
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Very high affinity and selective melatonin receptor agonist
| Product Type | Agonist |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Synonym | Ramelteon |
| Molecular Formula | C16H21NO2 |
| Formula Weight | 259.34 |
Tocris Bioscience™ Proglumide sodium salt
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Greener Choice
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CAS: 99247-33-3 Molecular Formula: C18H25N2NaO4
| CAS | 99247-33-3 |
|---|---|
| Molecular Formula | C18H25N2NaO4 |
Tocris Bioscience™ Bropirimine
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CAS: 56741-95-8 Molecular Formula: C10H8BrN3O
| CAS | 56741-95-8 |
|---|---|
| Molecular Formula | C10H8BrN3O |
Tocris Bioscience™ AEE 788
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Potent EGFR and VEGFR inhibitor
| Inhibitors | AEE 788 |
|---|---|
| Product Type | AEE 788 |
| Molecular Weight (g/mol) | 440.58 |
| Purity | >98% |
Tocris Bioscience™ Aliskiren hemifumarate
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Potent renin inhibitor; antihypertensive
| Product Type | Aliskiren hemifumarate |
|---|---|
| Molecular Weight (g/mol) | 609.83 |
| Purity | >99% |
Tocris Bioscience™ A 410099.1 amide-PEG4-amine
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IAP ligand with PEG linker and terminal amine for onward chemistry
Tocris Bioscience™ Lenalidomide 4'-alkylC3-azide
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Cereblon ligand with alkyl linker and terminal azide for onward chemistry
Tocris Bioscience™ MD15
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Negative control for MD13 (Cat. No. 7503)
Tocris Bioscience™ XAP 044
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Potent and selective mGlu7 antagonist
| Inhibitors | XAP 044 |
|---|---|
| Product Type | XAP 044 |
| Molecular Weight (g/mol) | 380.13 |
| Purity | >98% |